A 5-year sensitivity analysis of a recent trial showed improved efficacy outcomes and toxicity profiles for patients receiving a new adjuvant therapy for HER2-positive breast cancer. READ MORE

Conferences

Genomic analysis revealed differences in the landscape of estrogen receptor-positive cancers when compared with ER+ primary tumors.

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Observation for adverse reactions following trastuzumab serves as an unnecessary use of health resources.

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Common menopausal symptoms can be used as predictive tools for adherence to the aromatase inhibitor tamoxifen.

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Investigators reported results from a clinical trial comparing accelerated partial breast irradiation with whole breast irradiation.

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News

A 5-year sensitivity analysis of a recent trial showed improved efficacy outcomes and toxicity profiles for patients receiving a new adjuvant therapy for HER2-positive breast cancer.

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Factors predicting HER2 discordance between primary tumor and circulating tumor cells may be used as a surrogate for tumor biology and tumor heterogeneity in patients with breast cancer.

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Researchers examined whether low levels of pre-existing cytotoxic tumor-infiltrating lymphocytes can predict the response to antibody- and molecule-based drugs in metastatic HER2-positive breast cancer.

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Halting adjuvant endocrine therapy for ER-positive breast cancer after 5 years does not reduce the risk of cancer recurrence in the long-term.

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Research in Review

An immuno-agent improves PFS and lowers the risk of death for patients with HER2-negative metastatic breast cancer and a germline BRCA mutation.

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A low level of stromal cytotoxic T-cell infiltration in breast cancer tumor specimens predicts patients who may benefit most from antibody- vs molecular-based HER2 inhibitors.

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A neoadjuvant chemotherapy combination used to treat breast cancer increases the risk of disease metastasis.

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In younger women with hormone receptor-positive breast cancer, ovarian function suppression after surgery drives large improvements in breast cancer-free interval when combined with drug therapy.

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