Reviewing the Latest Research on Value-Based Care, Clinical Pathways, and Precision Medicine

High Risk of Preventable and Mitigable Adverse Events in Cancer Care

Researchers have identified a significant burden of adverse events across the cancer care continuum, including preventable or mitigable events.

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Breast Cancer Survival Outcomes After Mastectomy vs Breast-Conserving Surgery

A recent comparative effectiveness study examined long-term survival outcomes for patients with multiple stages of breast cancer after undergoing either mastectomy or breast-conserving surgery.

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Genetic Testing Underutilized in Women With History of Ovarian Cancer

Less than 20% of patients with a history of ovarian cancer meeting NCCN guidelines have undergone genetic testing or have discussed testing with their health care providers. 

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Aggressive Local Therapy Improves Outcomes in Patients With Head, Neck Cancer

A recent study uncovered the benefits of adding high-intensity local treatment to systemic therapy for head and neck squamous cell carcinoma.

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Resistance Mutations Predict Metastatic Patients in NSCLC

Specific gene rearrangements associated with increased resistance to standard therapy may predict different metastasis distributions in patients with non-small cell lung cancer.

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Financial Burden of ACPA Status in Patients With Rheumatoid Arthritis

A recent comparative effectiveness study examined the relationship of anticitrullinated protein antibody status and accrued economic burden for patients with rheumatoid arthritis.

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Comparative Effectiveness Study Evaluates Options for DLBCL

A recent study compared the treatment effects and adverse events of first-line chemotherapy regimens in patients with treatment-naïve diffuse large B-cell lymphoma.

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Pancreatic Cancer Guidelines Do Not Cover Some Targetable Mutations

Germline mutations in pancreatic cancer susceptibility genes are often identified in patients with pancreatic cancer without a known family history of cancer.

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Novel Prostate Cancer Biomarkers May Improve Targeted Therapy

Research uncovered a new cause of treatment resistance in prostate cancer, which may improve targeted therapy efforts.

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Standard of Care Breakthrough in Platinum-Sensitive Ovarian Cancer

Patients with ovarian cancer who are responsive to platinum-based chemotherapy may experience more than double an increase in PFS with a specific maintenance therapy, regardless of their disease characterization.

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